Pediatric Migraine Study

Ten percent of school age children have migraine, and it can be associated with significant functional disability, such as missing school, sports, social and family time.  Girls and boys have about the same incidence of migraine until puberty, when it increases in girls and remains stable or decreases in boys.  Non-pharmacologic tenants of good migraine management include adequate sleep, proper hydration, exercise, health foods, and learning how to manage stress. Non-pharmacologic interventions at our center include education in diet, sleep hygiene, exercise and stress management, biofeedback, cognitive-behavioral therapy, physical therapy and massage.

Some migraines, however, simply require medicines.  While over-the-counter analgesics like Ibuprofen may help a low-level headache, true migraine often needs better, more specific therapy.  While we have a number of good options for adults, there are not that many migraine-specific treatment choices for children and adolescents.  Our pediatric migraine research program aims to change that, and bring safe, effective and well-tolerated pediatric migraine treatments to the market.  Our current and upcoming studies include:


  • Zolmitriptan nasal spray is an effective acute migraine medicine approved in teens and adults.  The ROCKET study is testing an investigational nasal spray for kids 6-11 years old to see if it can help stop the pain caused by a migraine.  After a double-blind phase (with a chance of getting either the real zolmitriptan spray or a placebo spray), everyone can roll over to the open-label study, in which all participants receive the actual medicine.     Learn More


All studies at NEICR are available at no cost to you, and there may be compensation for time and travel.  Participation is completely voluntary, and you may withdraw at any time. To find out more about any of our studies, give us a call at 203-914-1903 or fill out the form below.

Use the form below to enroll

Pediatric Migraine - Clinical Study Enrollment