Migraine Headaches

Migraine is a chronic medical condition affecting an estimated 38 million people in the United States.  Throbbing, often one-sided moderate-to-severe head pain, accompanied by light and sound sensitivity and nausea/vomiting are the most common symptoms.  Some migraine sufferers experience dizziness, visual symptoms, numbness or weakness on one side of the body, slowed thinking or trouble speaking.

Migraine predominantly effects young and middle-aged woman (that is, during their prime work and child-rearing years), though it can strike men and children as well. When untreated, the World Health Organization lists migraine as among the top ten most disabling medical conditions.

Our migraine research program aims to find better acute and preventive treatments for adults and children who suffer from migraine. Our current and upcoming studies include:

  • This migraine trial is looking into a new, nasal spray, headache-stopping medication. The medication is a small molecule CGRP blocker meant for the acute treatment of migraine. This study is an open label study, meaning that there is no placebo and everyone who qualifies for the study will get the active study medication. This study will last for about a year, with qualified patients getting 8 doses of the study medication per month. Click the button to view information about this study on clinicaltrials.gov.   Learn More
  • We are currently conducting a trial looking into the preventative treatment of migraine in people with Major Depressive Disorder. This study begins with a three-month, double blind period. The study medication is an injection that will last for about one month. After this first phase of the study, is an open label period where you will receive the study medication for another three months. Click the button to view more information about this study on clinicaltrials.gov.   Learn More
  • Our site is offering a migraine trial for patients who are employed and suffer from migraines. This study is looking to see if the study medication influences workplace disability and work productivity. The study medication being tested in this trial has already been approved by the FDA for the prevention of migraines in adults.  Click the button to view information about this study on clinicaltrials.gov.    Learn More
  • Another trial we have for those who don’t like pills or shots, is a trial that is testing a device for medication delivery. In this trial, the device uses a small catheter placed deep in the nose to instill a tiny spray of medicine onto the SPG, a pain nerve that sits between the nose and brain.  This study is for those with Chronic Migraine (15 or more headache days per month). Click the button to view information about this study on clinicaltrials.gov.    Learn More

All studies at NEICR are available at no cost to you, and there may be compensation for time and travel.  Participation is completely voluntary, and you may withdraw at any time. To find out more about any of our studies, give us a call at 203-914-1903 or fill out the form below.

Use the form below to enroll

Adult Migraine - Clinical Study Enrollment