Pediatric Migraine Study

Ten percent of school age children have migraine, and it can be associated with significant functional disability, such as missing school, sports, social and family time.  Girls and boys have about the same incidence of migraine until puberty, when it increases in girls and remains stable or decreases in boys.  Non-pharmacologic tenants of good migraine management include adequate sleep, proper hydration, exercise, health foods, and learning how to manage stress. Non-pharmacologic interventions at our center include education in diet, sleep hygiene, exercise and stress management, biofeedback, cognitive-behavioral therapy, physical therapy and massage.

Some migraines, however, simply require medicines.  While over-the-counter analgesics like Ibuprofen may help a low-level headache, true migraine often needs better, more specific therapy.  While we have a number of good options for adults, there are not that many migraine-specific treatment choices for children and adolescents.  Our pediatric migraine research program aims to change that, and bring safe, effective and well-tolerated pediatric migraine treatments to the market.  Our current and upcoming studies include:

 

  • Zolmitriptan ROCKET study. Zolmitriptan nasal spray is an effective acute migraine medicine approved in teens and adults.  The ROCKET study is testing an investigational nasal spray for kids 6-11 years old to see if it can help stop the pain caused by a migraine.  After a double-blind phase (with a chance of getting either the real zolmitriptan spray or a placebo spray), everyone can roll over to the open-label study, in which all participants receive the actual medicine.     Learn More
  • Avanir Onzetra Xsail study. Onzetra Xsail is a unique way to deliver sumatriptan (a safe and effective compound that has been approved for over 20 years). The sumatriptan is made into a fine powder, and subjects blow into a small device, which propels the medicine deep into the nose. This allows for lower dose of medicine and less side-effects when compared to the pill form.  Onzetra Xsail was recently approved in adults, and this study seeks to prove that it is effective, safe and well-tolerated in adolescents (ages 12-17).     Learn More

 

Use the form below to enroll

Pediatric Migraine - Clinical Study Enrollment
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