Cluster Headache Study

Cluster headache (CH) has been described as one of the most painful conditions a human can experience.  Its nickname, suicide headache, accurately conveys the sentiment many cluster patients feel when in a cluster cycle. CH can be divided into to groups: those that cluster (that is, the headaches occur for weeks, are then gone for many months, then return.  This is called episodic cluster), and those that no longer cluster (chronic cluster), but rather occur every day without interruption.  Acute therapies include inhaled oxygen and sumatriptan injections, but there are no preventive treatments currently approved by the Food and Drug Administration (FDA).

At NEICR we have several exciting trials for cluster headache.

  • For chronic cluster, involves a tiny stimulator device surgically implanted through the upper gum into an area at the back of the nose and next to a pain sensory nerve complex called the SPG.  A hand-held device is used to deliver a small electric current to the stimulator to turn off the cluster attack.  The study is called, “Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache”.
    Learn more
  • Both Lilly pharmaceuticals and Teva pharmaceuticals have studies of monthly injections of a CGRP monoclonal antibody for both episodic and chronic cluster headaches.
    Learn more (Lilly) Learn more (Teva)

These and all studies at NEICR are free, and there is compensation provided for time and travel.  To enroll or learn more fill out the form below or call us at 203-914-1903.

Use the form below to enroll

Cluster Headache - Clinical Study Enrollment